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Senior Scientist, Cell Biology

Company: zPREDICTA, a Predictive Oncology company
Location: San Jose
Posted on: January 16, 2022

Job Description:

JOB DESCRIPTION

Founded with the mission to enable successful treatments for every patient, zPREDICTA, a Predictive Oncology Company, has developed organ-specific 3D cell culture technology replicating human tumor microenvironment for reliable identification of compounds with a high probability of success in the clinic. You will join a dynamic and agile team developing 3D tissue models to support anticancer drug development. You will be responsible for building a scientific team, directing internal R&D and external partner projects from conceptualization to execution, and contributing to the growth of zPREDICTA brand.

To be successful, you have to be excited by the fast-paced environment, be engaged while performing multiple roles, and possess a versatile set of technical skills. zPREDICTA offers competitive compensation and benefits package, including medical, dental, vision, and 401k with matching, as well as equity ownership. You will have an opportunity to work side-by-side with the leadership team in a highly collaborative environment.

KEY RESPONSIBILITIES
Design, develop, and implement new organ-specific 3D tissue models for target discovery and efficacy and toxicity testing of anticancer agents
Build and grow a versatile scientific team responsible for R&D and partner projects
Participate in client meetings and prepare study plans and project budgets
Support partner projects from study design through data analysis and report preparation

EDUCATION
Ph.D. in Cell Biology, Immunology, or related life science discipline, AND
2-5 years of industry experience; start-up experience is a plus

REQUIRED EXPERIENCE
Working knowledge of tumor biology and therapeutic trends
In depth knowledge tumor microenvironment, specifically ECM and cellular heterogeneity
Skilled in various cell culture methods: 2D, 3D, tumor-stroma-immune cell co-cultures
Experience working with immuno-oncology agents
Expertise in scaffold-based 3D cell culture
Experience with various types of microscopy
Knowledge of image processing and analysis packages (ImageJ. Photoshop)
Expertise in assay development and optimization.
Experience setting-up SOPs and developing protocols and procedures

PREFERRED EXPERIENCE
Cell culture of primary mammalian cells
PDX models and culture of PDX tissue
Organ-on-a-chip and/or microfluidic devices
Organoid generation
Flow cytometry

PERSONAL CHARACTERISTICS
Self-starter and innovator
Team leader with creative ideas
Focused, but capable of driving multiple projects
Curious and independent thinker driven to solve problems
Unafraid of working outside of the area of expertise and experimenting with new approaches
Roll-up-your-sleeves and jump-in attitude
Appreciate a fast-paced environment
Enjoy teaching and learning

CANDIDATE MUST HAVE APPROPRIATE WORK AUTHORIZATION TO WORK IN THE UNITED STATES.
This position does not offer immigration visa sponsorship.
This position does not offer relocation benefits.

zPREDICTA -is an equal opportunity employer.

Keywords: zPREDICTA, a Predictive Oncology company, San Jose , Senior Scientist, Cell Biology, Other , San Jose, California

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