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Research Associate (RA)

Company: Accellix
Location: San Jose
Posted on: February 23, 2021

Job Description:

Personalized, cell-based therapy is emerging as a paradigm-shifting strategy in healthcare. To harness the potential of cutting-edge cellular engineering, stringent process controls must be put into place that monitor and measure critical parameters of the cell product at every step, from patient sample acquisition to drug product release. In essence, the process is the product.The Accellix system offers a streamlined workflow solution that couples automated sample preparation within a single-use microfluidic cartridge, customized ambient-stable reagents, high sensitivity fluorescent event detection, and assay-specific auto analysis.--The combination results in robust multiparametric analysis with 'mix and read' simplicity, enabling standardized process controls for engineered T-cells and other cell therapy products.We are seeking highly motivated individuals ideally with fluorescence-based assay development experience. The candidates will join an interdisciplinary team to migrate and optimize traditional flow cytometry assays onto the Accellix platform. In addition, the candidates will be actively involved in the design and implementation of manufacturing and QC protocols for reagent formulation and consumables, under a growing quality system. Responsibilities* Assist in developing and optimizing fluorescence-based cell classification, enumeration, and cell function assays to meet the specific needs of our cell-therapy customers* Establish and refine good manufacturing processes, generate associated documentation, and participate in tech transfer* Work with cross-functional teams to integrate assays onto the Accellix platform, and ensure assay requirements are met* Promote a strong working relationship with others in the lab to encourage efficiency, communication, and teamworkQualifications* B.S with 2-4 years of relevant industry experience* Basic knowledge of flow cytometry and other fluorescence-based methodologies* Experience in reagent formulation under GMP is highly desired* Experience with integrating assays onto automated instruments, design and testing of assay consumables, or in vitro diagnostics would be a big plus* Demonstrated experience in managing multiple projects* Prepared to be highly engaged and pro-active, both within the team and within the company

Keywords: Accellix, San Jose , Research Associate (RA), Other , San Jose, California

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