Research Associate (RA)
Company: Accellix
Location: San Jose
Posted on: February 23, 2021
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Job Description:
Personalized, cell-based therapy is emerging as a
paradigm-shifting strategy in healthcare. To harness the potential
of cutting-edge cellular engineering, stringent process controls
must be put into place that monitor and measure critical parameters
of the cell product at every step, from patient sample acquisition
to drug product release. In essence, the process is the product.The
Accellix system offers a streamlined workflow solution that couples
automated sample preparation within a single-use microfluidic
cartridge, customized ambient-stable reagents, high sensitivity
fluorescent event detection, and assay-specific auto analysis.--The
combination results in robust multiparametric analysis with 'mix
and read' simplicity, enabling standardized process controls for
engineered T-cells and other cell therapy products.We are seeking
highly motivated individuals ideally with fluorescence-based assay
development experience. The candidates will join an
interdisciplinary team to migrate and optimize traditional flow
cytometry assays onto the Accellix platform. In addition, the
candidates will be actively involved in the design and
implementation of manufacturing and QC protocols for reagent
formulation and consumables, under a growing quality system.
Responsibilities* Assist in developing and optimizing
fluorescence-based cell classification, enumeration, and cell
function assays to meet the specific needs of our cell-therapy
customers* Establish and refine good manufacturing processes,
generate associated documentation, and participate in tech
transfer* Work with cross-functional teams to integrate assays onto
the Accellix platform, and ensure assay requirements are met*
Promote a strong working relationship with others in the lab to
encourage efficiency, communication, and teamworkQualifications*
B.S with 2-4 years of relevant industry experience* Basic knowledge
of flow cytometry and other fluorescence-based methodologies*
Experience in reagent formulation under GMP is highly desired*
Experience with integrating assays onto automated instruments,
design and testing of assay consumables, or in vitro diagnostics
would be a big plus* Demonstrated experience in managing multiple
projects* Prepared to be highly engaged and pro-active, both within
the team and within the company
Keywords: Accellix, San Jose , Research Associate (RA), Other , San Jose, California
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